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Outcomes of Pregnancies with Laboratory Evidence of Possible Zika Virus Infection in the United States and the US Territories*


Outcomes for Completed Pregnancies in the US States, the District of Columbia, and the US Territories*+

* Includes US Territories and Freely Associated States

+ Em 13 de junho de 2017

Outcomes for US States and the District of Columbia

Gestações concluídas com ou sem defeitos congênitos

1,654

Includes aggregated data reported to the US Zika Pregnancy Registry

Liveborn infants with birth defects

80

Includes aggregated data reported to the US Zika Pregnancy Registry

Gestações perdidas com defeitos congênitos.

8

Includes aggregated data reported to the US Zika Pregnancy Registry

Outcomes for US Territories*

Gestações concluídas com ou sem defeitos congênitos

2,697

Includes aggregated data reported to the Zika pregnancy and infant registries

Liveborn infants with birth defects

122

Includes aggregated data reported to the Zika pregnancy and infant registries

Gestações perdidas com defeitos congênitos.

6

Includes aggregated data reported to the Zika pregnancy and infant registries

Sobre esses números

O que esses números mostram

  • O número de gestações concluídas com ou sem defeitos congênitos inclui as que terminaram com o bebê vivo, com aborto espontâneo, com o bebê natimorto ou com interrupção.
  • The number of liveborn infants and pregnancy losses with birth defects include those among completed pregnancies with laboratory evidence of possible Zika virus infection.
  • The numbers are aggregated into two categories 1) the 50 US states and the District of Columbia, and 2) the US territories and freely associated states. At this time, CDC is not reporting individual state, tribal, territorial or jurisdictional data to protect the privacy of the women and children affected by Zika. CDC is using the standard CDC surveillance case definition for the Zika Pregnancy and Infant registries to monitor brain abnormalities, microcephaly, and other serious birth defects that have been linked to Zika virus infection during pregnancy across the United States and territories.
  • The numbers may increase or decrease as new cases are added or information on existing cases is clarified.
  • Birth defects reported include those that have been linked to Zika virus infection during pregnancy, including microcephaly, calcium deposits in the brain indicating possible brain damage, excess fluid in the brain cavities and surrounding the brain, absent or poorly formed brain structures, abnormal eye development, or other problems resulting from damage to brain that affects nerves, muscles and bones, such as clubfoot or inflexible joints, and confirmed hearing loss.

O que esses novos números não mostram

  • These numbers reflect the outcomes of pregnancies with any laboratory evidence of possible Zika virus infection reported to the Zika pregnancy and infant registries as of the date specified. There may be delays in reporting of pregnancy outcomes from the jurisdictions.
  • Although these birth defects occurred from pregnancies of women with laboratory evidence of possible Zika virus infection, we cannot determine whether individual defects were caused by Zika virus infection or other factors.

De onde vêm esses números?

  • These data reflect pregnancies reported to the Zika pregnancy and infant registries. Together, these registries cover the full United States including territories and freely associated states.
  • These systems were established in collaboration with state, local, tribal and territorial health departments for comprehensive monitoring of pregnancy and infant outcomes of pregnancies with any laboratory evidence of possible Zika virus infection.
  • The data collected through the Zika pregnancy and infant registries will be used to update recommendations for clinical care, to plan for services and support for pregnant women and families affected by Zika virus, and to improve prevention of Zika virus infection during pregnancy.
  • The Zika Pregnancy and Infant Registries) are protected by an Assurance of Confidentiality. Under the Assurance, CDC cannot report jurisdiction-specific information without permission from the jurisdiction.

Critérios de inclusão de casos detalhados para profissionais de saúde

As informações a seguir detalham os critérios de inclusão para anormalidades cerebrais e outros resultados adversos potencialmente relacionados à infecção pelo zika vírus durante a gravidez. All pregnancy outcomes are monitored, but reporting of adverse outcomes is limited to those meeting the criteria below.


Anormalidades cerebrais com e sem microcefalia

  • Microcefalia congênita possível ou confirmada#
  • Calcificações intracranianas
  • Atrofia cerebral
  • Formação cortical anormal (ex.: polimicrogiria, lissencefalia, paquigiria, esquizencefalia, heterotopia da massa cinzenta)
  • Anormalidades no corpo caloso
  • Anormalidades cerebelares
  • Porencefalia
  • Hidranencefalia
  • Ventriculomegalia/hidrocefalia (exceto ventriculomegalia "moderada" sem outras anormalidades cerebrais)
  • Sequência de disrupção cerebral fetal (crânio afundado, suturas sobrepostas, osso occipital proeminente, couro cabeludo rugoso)
  • Outras importantes anormalidades cerebrais, incluindo hemorragia intraventricular no útero (exceto IVH pós-natal).


Defeitos no tubo neural e outras malformações cerebrais precoces

  • Defeitos no tubo neural (DTN)
    • Anencefalia/acrania
    • Encefalocele
    • Espinha bífida
  • Holoprosencefalia/arrinencefalia


Anormalidades oculares estruturais

  • Microftalmia/anoftalmia
  • Coloboma
  • Catarata
  • Calcificações intraoculares
  • Anomalias coriorretiniana envolvendo a mácula (ex.: atrofia coriorretinal e cicatrizes, palidez macular, mancha com pigmentação aparente e hemorragia retiniana), exceto retinopatia e prematuridade
  • Palidez, atrofia do nervo óptico e outras anormalidades do nervo óptico


Consequências de disfunção no sistema nervoso central (SNC)

  • Contraturas congênitas (ex.: artrogripose, pé torto, displasia congênita do quadril) com anormalidades cerebrais associadas
  • Surdez congênita documentada por teste pós-natal.

 

#Live births: measured head circumference (HC) adjusted for gestational age and sex <3rd percentile at birth, or if not measured at birth, within first 2 weeks of life; pregnancy loss: prenatal HC more than 3 standard deviations below the mean based on ultrasound or postnatal HC <3rd percentile. As medições ao nascer são baseadas nos padrões intergrowth21, que são baseados nas medições dentro de 24 horas após o nascimento e, portanto, medições dentro de 24 horas após o nascimento são apropriadas para essa avaliação.

INÍCIO